Published Journal Articles

The following research has been published as a result of work from the ARMMS-T2D consortium:

Simonson DC, Hu B, Arterburn DE, Schauer PR, Kashyap SR, Courcoulas AP, Cummings DE, Patti ME, Gourash WF, Vernon AH, Jakicic JM, Kirwan JP. (2022, July). Alliance of Randomized Trials of Medicine vs Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D): Study rationale, design, and methods. Diabetes, Obesity and Metabolism 24(7), 1206-1215 doi:10.1111/dom.14680.

https://pubmed.ncbi.nlm.nih.gov/35233923/

Kirwan JP, Courcoulas AP, Cummings DE, Goldfine AB, Kashyap SR, Simonson DC, Arterburn DE, Gourash WF, Vernon AH, Jakicic JM, Patti ME, Wolski K, Schauer PR. (2022, March). Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D). Diabetes Care doi:10.2337/dc21-2441.

https://pubmed.ncbi.nlm.nih.gov/35320365/

Lorkowski SW, Brubaker G, Rotroff DM, Kashyap SR, Bhatt DL, Nissen SE, Schauer PR, Aminian A, Smith JD. (2020, April). Bariatric Surgery Improves HDL Function Examined by ApoA1 Exchange Rate and Cholesterol Efflux Capacity in Patients with Obesity and Type 2 Diabetes. Biomolecules 10(4), 551 doi:10.3390/biom10040551.

https://pubmed.ncbi.nlm.nih.gov/32260470/

Courcoulas AP, Gallagher JW, Neiberg RH, Eagleton EB, DeLany JP, Lang W, Punchai S, Gourash W, Jakicic JM. (2020, March). Bariatric Surgery vs Lifestyle Intervention for Diabetes Treatment: 5-Year Outcomes From a Randomized Trial. J Clin Endocrinol Metab 105(3) doi:10.1210/clinem/dgaa006.

https://www.ncbi.nlm.nih.gov/pubmed/31917447

Simonson DC, Vernon A, Foster K, Halperin F, Patti ME, Goldfine AB. (2019, December). Adjustable gastric band surgery or medical management in patients with type 2 diabetes and obesity: three-year results of a randomized trial. Surg Obes Relat Dis 15(12), 2052-2059 doi:10.1016/j.soard.2019.03.038. Epub 2019 Apr 16.

https://pubmed.ncbi.nlm.nih.gov/31931977/

Bhatt DL, Aminian A, Kashyap S, Kirwan J, Wolski K, Brethauer SA, Hazen S, Nissen S, Schauer PR. (2019, July). Cardiovascular Biomarkers After Metabolic Surgery Versus Medical Therapy for Diabetes. J Am Coll Cardiol 74(2), 261-263 doi:10.1016/j.jacc.2019.04.058.

https://www.ncbi.nlm.nih.gov/pubmed/31296299

Zhou K, Wolski K, Malin SK, Aminian A, Schauer PR, Bhatt DL, Kashyap SR. (2019, June). Impact of Weight Loss Trajectory Following Randomization to Bariatric Surgery on Long-Term Diabetes Glycemic and Cardiometabolic Parameters. Endocr Pract 25(6), 572-579 doi:10.4158/EP-2018-0522.

https://www.ncbi.nlm.nih.gov/pubmed/30865529

Simonson DC, Halperin F, Foster K, Vernon A, Goldfine AB. (2018, April). Clinical and Patient-Centered Outcomes in Obese Patients with Type 2 Diabetes 3 Years After Randomization to Roux-en-Y Gastric Bypass Surgery Versus Intensive Lifestyle Management: The SLIMM-T2D Study. Diabetes Care 41(4), 670-679 doi:10.2337/dc17-0487.

https://www.ncbi.nlm.nih.gov/pubmed/29432125

Crawford MR, Pham N, Khan L, Bena JF, Schauer PR, Kashyap SR. (2018, March). Increased Bone Turnover in Type 2 Diabetes Patients Randomized to Bariatric Surgery vs. Medical Therapy at 5 Years. Endocr Pract 24(3), 256-264 doi:10.4148/EP-2017-0072.

https://www.ncbi.nlm.nih.gov/pubmed/29144812

Pham NH, Bena J, Bhatt DL, Kennedy L, Schauer PR, Kashyap SR. (2018, January). Increased Free Testosterone Levels in Men with Uncontrolled Type 2 Diabetes Five Years After Randomization to Bariatric Surgery. Obes Surg 28(1), 277-280 doi:10.1007/s11695-017-2881-5.

https://www.ncbi.nlm.nih.gov/pubmed/29143290

Banerjee S, Garrison LP, Flum DR, Arterbrun DE. (2017, September). Cost and Health Care Utilization Implications of Bariatric Surgery Versus Intensive Lifestyle and Medical Intervention for Type 2 Diabetes. Obesity (Silver Spring) 25(9), 1499-1508 doi:10.1002/oby.21927.

https://www.ncbi.nlm.nih.gov/pubmed/28722299

Kheniser KG, Kashyap SR, Schauer PR, Lam ETC, Kullman ES. (2017, May). Prevalence of Anemia in Subjects Randomized into Roux-en-Y Gastric Bypass or Sleeve Gastrectomy. Obes Surg 27(5), 1381-1386 doi:10.1007/s11695-017-2563-1.

https://www.ncbi.nlm.nih.gov/pubmed/28185151

Schauer PR, Bhatt DL, Kashyap SR. (2017, May). Bariatric Surgery or Intensive Medical Therapy for Diabetes after 5 Years. N Engl J Med 376(20), 1997 doi:10.1056/NEJMc1703377.

https://www.ncbi.nlm.nih.gov/pubmed/28514616

Crawford MR, Bena JF, Schauer PR, Kashyap SR. (2017, April). Long term outcomes of bariatric surgery on bone density in obese patients with type 2 diabetes. J Diabetes Complications 31(4), 780-781 doi:10.1016/j.jdiacomp.2017.01.009.

https://www.ncbi.nlm.nih.gov/pubmed/28139344

Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Aminian A, Brethauer SA, Navaneethan SD, Singh RP, Pothier CE, Nissen SE, Kashyap SR. (2017, February). Bariatric Surgery versus Intensive Medical Therapy for Diabetes - 5-Year Outcomes. N Engl J Med 376(7), 641-651 doi:10.1056/NEJMoa1600869.

https://www.ncbi.nlm.nih.gov/pubmed/28199805

Panosian J, Ding SA, Simonson DC, Goebel-Fabbri A, Foster K, Halperin F, Vernon A, Goldfine AB. (2016, August). Physical Activity in Obese Type 2 Diabetes After Gastric Bypass or Medical Management. Am J Med 130(1), 83-92 doi:10.1016/j.amjmed.2016.07.019.

https://www.ncbi.nlm.nih.gov/pubmed/27555097

Cummings DE, Arterburn DE, Westbrook EO, Kuzma JN, Stewart SD, Chan CP, Bock SN, Landers JT, Kratz M, Foster-Schubert KE, Flum DR. (2016, March). Gastric bypass surgery vs intensive lifestyle and medical intervention for type 2 diabetes: the CROSSROADS randomised controlled trial. Diabetologia 59(5), 945-953 doi:10.1007/s00125-016-3903-x.

https://www.ncbi.nlm.nih.gov/pubmed/26983924

Yu EW, Wewalka M, Ding SA, Simonson DC, Foster K, Holst JJ, Vernon A, Goldfine AB, Halperin F. (2016, February). Effects of Gastric Bypass and Gastric Banding on Bone Remodeling in Obese Patients with Type 2 Diabetes. J Clin Endocrinol Metab 101(2), 714-722 doi:10.1210/jc.2015-3437.

https://www.ncbi.nlm.nih.gov/pubmed/26600045

Maghrabi AH, Wolski K, Abode B, Licata A, Pothier C, Bhatt D, Nissen S, Brethauer SA, Kirwan JP, Schauer PR, Kashyap SR. (2015, December). Two-year outcomes on bone density and fracture incidence in patients with T2DM randomized to bariatric surgery versus intensive medical therapy. Obesity (Silver Spring) 23(12), 2344-2348 doi:10.1002/oby.21150.

https://www.ncbi.nlm.nih.gov/pubmed/26193177

Courcoulas AP, Belle SH, Neiberg RH, Pierson SK, Eagleton JK, Kalarchian MA, DeLany JP, Lang W, Jakicic JM. (2015, October). Three-Year Outcomes of Bariatric Surgery vs Lifestyle Intervention for Type 2 Diabetes Mellitus Treatment: A Randomized Clinical Trial. JAMA Surg 150(10), 931-940 doi:10.1001/jamasurg.2015.1534.

https://www.ncbi.nlm.nih.gov/pubmed/26132586

Ding SA, Simonson DC, Wewalka M, Halperin F, Foster K, Goebel-Fabbri A, Hamdy O, Clancy K, Lautz D, Vernon A, Goldfine AB. (2015, July). Adjustable Gastric Band Surgery or Medical Management in Patients With Type 2 Diabetes: A Randomized Clinical Trial. J Clin Endocrinol Metab 100(7), 2546-2556 doi:10.1210/jc.2015-1443.

https://www.ncbi.nlm.nih.gov/pubmed/25909333

Singh RP, Gans R, Kashyap SR, Bedi R, Wolski K, Brethauer S, Nissen S, Bhatt DL, Schauer PR. (2015, March). Effect of bariatric surgery vs. intensive medical management on diabetic ophthalmic outcomes. Diabetes Care 38(3), e32–e33 doi:10.2337/dc14-2035.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338505/

Khanna V, Malign SK, Bean J, Abode B, Pothier CE, Bhatt DL, Nissen S, Watanabe R, Brethauer SA, Schauer PR, Kirwan JP, Kashyap SR. (2015, March). Adults with long-duration type 2 diabetes have blunted glycemic and β-cell function improvements after bariatric surgery. Obesity (Silver Spring) 23(3), 523-526 doi:10.1002/oby.21021.

https://www.ncbi.nlm.nih.gov/pubmed/25651277

Malin SK, Bena J, Abood B, Pothier CE, Bhatt DL, Nissen S, Brethauer SA, Schauer PR, Kirwan JP, Kashyap SR. (2014, December). Attenuated improvements in adiponectin and fat loss characterize type 2 diabetes non-remission status after bariatric surgery. Diabetes Obes Metab 16(12), 1230-1238 doi:10.1111/dom.12376.

https://www.ncbi.nlm.nih.gov/pubmed/25132119

Schauer PR, Bhatt DL, Kashyap SR. (2014, August). Bariatric surgery versus intensive medical therapy for diabetes. N Engl J Med 371(7), 682 doi:10.1056/NEJMc1407393.

https://www.ncbi.nlm.nih.gov/pubmed/25119615

Halperin F, Ding SA, Simonson DC, Panosian J, Goebel-Fabbri A, Wewalka M, Hamdy O, Abrahamson M, Clancy K, Foster K, Lautz D, Vernon A, Goldfine AB. (2014, July). Roux-en-Y gastric bypass surgery or lifestyle with intensive medical management in patients with type 2 diabetes: feasibility and 1-year results of a randomized clinical trial. JAMA Surg 149(7), 716-726 doi:10.1001/jamasurg.2014.514.

https://www.ncbi.nlm.nih.gov/pubmed/24899464

Courcoulas AP, Goodpaster BH, Eagleton JK, Belle SH, Kalarchian MA, Lang W5, Toledo FG, Jakicic JM. (2014, July). Surgical vs medical treatments for type 2 diabetes mellitus: a randomized clinical trial. JAMA Surg 149(7), 707-715 doi:10.1001/jamasurg.2014.467.

https://www.ncbi.nlm.nih.gov/pubmed/24899268

Schauer PR, Bhatt DL, Kirwan JP, Wolski K, Brethauer SA, Navaneethan SD, Aminian A, Pothier CE, Kim ES, Nissen SE, Kashyap SR. (2014, May). Bariatric surgery versus intensive medical therapy for diabetes--3-year outcomes. N Engl J Med 370(21), 2002-2013 doi:10.1056/NEJMoa1401329.

https://www.ncbi.nlm.nih.gov/pubmed/24679060

Malin SK, Samar A, Wolski K, Abood B, Pothier CE, Bhatt DL, Nissen S, Brethauer SA, Schauer PR, Kirwan JP, Kashyap SR. (2014, March). Improved acrylate ghrelin suppression at 2 years in obese patients with type 2 diabetes: effects of bariatric surgery vs. standard medical therapy. Int J Obes (Lond) 38(3), 364-370 doi:10.1038/ijo.2013.196.

https://www.ncbi.nlm.nih.gov/pubmed/24166065

Arterburn D, Flum DR, Westbrook EO, Fuller S, Shea M, Bock SN, Landers J, Kowalski K, Turnbull E, Cummings DE. (2013, November). A population-based, shared decision-making approach to recuit for a randomized trial of bariatric surgery versus lifestyle for type 2 diabetes. Surg Obes Relat Dis 9(6), 837-844 doi:10.1016/j.soard.2013.05.006.

https://www.ncbi.nlm.nih.gov/pubmed/23911345

Kashyap SR, Bhatt DL, Wolski K, Watanabe RM, Abdul-Ghani M, Abood B, Pothier CE, Brethauer S, Nissen S, Gupta M, Kirwan JP, Schauer PR. (2013, August). Metabolic Effects of Bariatric Surgery in Patients With Moderate Obesity and Type 2 Diabetes: Analysis of a randomized control trial comparing surgery with intensive medical treatment. Diabetes Care 36(8), 2175-2182 doi:10.2337/dc12-1596.

https://www.ncbi.nlm.nih.gov/pubmed/23439632

Schauer PR, Kashyap SR, Wolski K, Brethauer SA, Kirwan JP, Pothier CE, Thomas S, Abood B, Nissen SE, Bhatt DL. (2012, April). Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 366(17), 1567-1576 doi:10.1056/NEJMoa1200225.

https://www.ncbi.nlm.nih.gov/pubmed/22449319

Kashyap SR, Bhatt DL, Schauer PR. (2010, May). Bariatric surgical procedures vs. advanced practice medical management in the treatment of type 2 diabetes mellitus: rationale and design of the Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently trial (STAMPEDE). Diabetes Obes Metab 12(5), 452-454 doi:10.1111/j.1463-1326.2009.01172.x.

https://www.ncbi.nlm.nih.gov/pubmed/20415694